Risk of liver fibrosis beyond a normal alanine aminotransferase level
نویسندگان
چکیده
منابع مشابه
Predictors for advanced liver fibrosis in chronic hepatitis B virus infection with persistently normal or mildly elevated alanine aminotransferase
The aim of the present study was to evaluate the predictors for advanced liver fibrosis in patients with chronic hepatitis B virus (HBV) infection with persistently normal alanine aminotransferase (PNALT), or persistently or intermittently mildly elevated ALT (PIEALT). A total of 305 patients were included in the present study. Liver biopsies were evaluated using the METAVIR scoring system. Liv...
متن کاملWhat is the normal serum alanine aminotransferase (ALT) value for Thai subjects with the low risk of liver diseases?
Background It still remains unclear whether the currently used normal range for serum alanine aminotransferase (ALT) levels really reflects a healthy liver. Objective To determine the thresholds for healthy ALT values or the normal value for Thai subjects with the low risk of liver diseases who participate in the annual physical checkup at King Chulalongkorn Memorial Hospital (KCMH). Materials ...
متن کاملAlanine Aminotransferase
An examination of the subcellular distribution of alanine aminotransferase activity in pig cardiac tissue showed that about 10% of the total activity was bound to particulate material, with the highest specific activity in the sarcosomal fraction. The soluble enzyme was obtained in a high state of purity, as indicated by sedimentation velocity, starch gel electrophoresis, and spectral analyses....
متن کاملUpper limit of normal for alanine aminotransferase: quo vadis?
Several studies suggest that a substantial number of patients with normal serum alanine aminotransferase (ALT) levels, defined by current thresholds, have ongoing hepatic necro-inflammation and fibrosis, and are at risk of liver disease progression. A major problem lies in the definition of normality. The current upper limit of normal (ULN) for ALT was established in the 1980s when reference po...
متن کاملLiver histology and HBV DNA levels in chronically HBV infected patients with persistently normal alanine aminotransferase.
BACKGROUND Data on histological activity and HBV DNA levels in patients with chronic HBV infection and persistently normal alanine aminotransferase levels are sparse. We aimed to investigate the histological activity and HBV DNA levels in these patients. METHODS There were 132 patients with HBeAg negative chronic HBV infection and persistently normal alanine aminotransferase levels that were ...
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ژورنال
عنوان ژورنال: Advances in Digestive Medicine
سال: 2019
ISSN: 2351-9797,2351-9800
DOI: 10.1002/aid2.13120